Mood, Sleep and Cognition Peptides

Generally speaking, it is normal to have days where you may feel happier than other days, or perhaps even sad. It is when these changes in mood begin to interfere with your every day life, or become extreme, that you may want to consult with a doctor to assess the underlying issue or what may be triggering them.

We all know that stress can cause many different issues, including being more short tempered, angry or even sad. On the other hand, mood swings or changes in behavior can also be a sign of a medical condition, especially if you are having them consistently or what seems, “out of your control”.

Some causes of rapid changes in behavior can be related to mental health, substance use, other health conditions, or hormones. If you experience extreme mood shifts, talk to your doctor about the best treatment plan for you.

Growth Hormone Releasing Hormone Peptides trigger the hypothalamus to release the bodies own stored growth hormone (GH).

DSIP (Delta Sleep Inducing Peptide) can act as a stress limiting factor as it increases sleep efficiency and shortens sleep latency. It has also been known to have anti-oxidant effects, and is beneficial for withdrawal symptoms of both alcohol and opioid use.

Selank & Semax are similar peptides in the melanocortin class that work in brain hormone signaling. They have been used to treat cognitive impairment, anxiety, depression, ADD/ADHD, metabolic syndrome, immune function, alcohol and benzodiazepine addiction.

Tesofensine was originally studied in patients with neurodegenerative diseases like Alzheimer’s and Parkinson’s and researchers found subjects were losing weight. This peptide increases serotonin, norepinephrine and dopamine which can help some patients with energy, mood, memory and weight.


  • Trouble sleeping
  • Feeling overwhelmed
  • Problems with memory
  • Problems concentrating
  • Change in eating habits
  • Feeling nervous or anxious
  • Feeling angry, irritable or easily frustrated
  • Feeling burned out from studying or schoolwork
  • Feeling that you can’t overcome difficulties in your life
  • Trouble functioning in class or in your personal life
  • Withdrawing from other people
  • Feeling sad and hopeless
  • Lack of energy, enthusiasm and motivation
  • Trouble making decisions
  • Being restless, agitated and irritable
  • Eating more or less than usual
  • Sleeping more or less than usual
  • Trouble concentrating
  • Trouble with memory
  • Feeling bad about yourself or feeling guilty
  • Anger and rage
  • Feeling that you can’t overcome difficulties in your life
  • Trouble functioning in your class or in your personal life
  • Thoughts of suicide


Sleep plays an important role in your physical health. Consecutive good night’s rest assists in the healing and repair of your heart and blood vessels, helps you maintain energy, focus and overall sense of well being. On the other hand, ongoing sleep deficiency is linked to an increased risk of heart disease, kidney disease, high blood pressure, diabetes, and stroke.

  • Numerous studies have found that insufficient sleep increases a person’s risk of developing serious medical conditions, including obesity, diabetes, and cardiovascular disease. Lack of consistent rest alters insulin resistance, which is associated with an increase of developing type 2 diabetes Lack of adequate sleep over time has been associated with a shortened lifespan.
  • For healthy adults, sleep is a key time for the release of human growth hormone. The biggest and most significant production of HGH happens during deep sleep, and serious sleep disruptions can interfere with the body’s normal process for releasing HGH into the bloodstream.
  • During every 24-hour period, the pituitary gland secretes growth hormone as a result of signaling from the hypothalamus, a part of the brain directly above the pituitary. The secretion of growth hormone is intermittent; it happens through roughly 6-10 pulses during each 24-hour period

According to the University of Michigan National Poll on Healthy Aging, more than two in five adults age 50–64 (44%) worry about developing progressive memory decline.

Memory Decline

The causes of cognitive decline can include toxins, stress, nutrient imbalances, genetic predisposition, traumatic brain injury, vascular changes and infections. Each situation is different and therefore there may be certain peptides, or perhaps more than one that could assist you on your pathway of increasing cognitive function. Some of the peptides prescribed to support health neuronal function can include:

LL-37, BPC-157, Selank, Semax, Dihexa.

As you already know, peptides are essential for the balance of hormones. They can also help you have a good night sleep. Peptide supplementation is excellent at regulating many body functions, and sleep is one of them.


There are incredible benefits to using peptides to help you sleep.

  • Promoting deep, regenerative sleep
  • Increases vivid dream state
  • Encourages delta wave sleep
  • More energy and better mood
  • Better response to stress
  • Prevents weight gain

“TBI or traumatic brain injury presents along a confusing and poorly understood continuum for the layperson and medical professionals alike. Although severe TBI is often publicized, mild and chronic TBIs are more costly as a whole and traditionally there has not been adequate treatment for these disabling conditions. Chronic TBI with all its confusing symptoms leads to divorce, disruption of the family and career, depression and hormonal abnormalities which literally steal life from the patient and family unit. With our elucidation of the persistent nature of neuroinflammation and the discovery of several nootropic peptides used for successful treatment of neurocognitive impairment we have a new, cutting-edge treatment available for tens of thousands of patients.” ~ Dr. Wesley Robinson

Scroll to Top